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Carbon–Heteroatom Bond Forming Reactions and Heterocycle Synthesis under Ball Milling

Ball-milling has received considerable attention in organic synthesis as reactions under ball milling can be performed in the absence of any solvent, at ambient temperature and under mild conditions, which are relevant for a green process. The carbon–heteroatom bond forming reactions and synthesis of heterocycles are of much importance in academia as well as pharmaceutical industry. The present chapter focuses on the carbon–heteroatom bond forming reactions (particularly C–N, C–O, C–S, C–Se, C–Te, C–F, C–Cl, C–I, etc.) and the synthesis of heterocycles (particularly N-, O- and B-containing heterocycles and macro-heterocycles) under ball-milling. Moreover, the oxygenation and cycloaddition reactions of fullerene leading to corresponding heterocycles are also included.

Publication details

Print publication date
05 Dec 2014
Copyright year
Print ISBN
ePub eISBN
From the book series:
Green Chemistry Series