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CHAPTER 27

Carnosine Protection Against Liver Injury

The role of carnosine in ameliorating liver injury has gained a great deal of interest recently. Although its use in humans is limited due to the presence of serum carnosinase, the efficiency of carnosine supplementation in liver diseases has been investigated in various animal models including ischemia–reperfusion, acetaminophen, thioacetamide, cadmium intoxication, sepsis, alcohol and nonalcoholic fatty liver. Its beneficial and protective actions as an antioxidative, anti-inflammatory, antiapoptotic, antifibrolitic and antiglycating agent are well established.

Publication details


Print publication date
13 Aug 2015
Copyright year
2015
Print ISBN
978-1-84973-890-3
PDF eISBN
978-1-78262-261-1
ePub eISBN
978-1-78262-655-8