The Concept of Multicatalysis in Aerobic Oxidation of Alcohols
The transition metal-catalyzed aerobic oxidation of alcohols is an amazing example of an environmentally friendly and efficient process using dioxygen (or air) as a simple and inexpensive oxidant, producing water as by-product. In some cases, cooperative catalysis introduces and provides large benefits for these transformations. This chapter highlights recent developments in multicatalytic systems for the aerobic oxidation of alcohols including biomimetic oxidation and synergistic bimetallic systems. The importance of catalytic aerobic oxidation in multistep reactions for the rapid and efficient construction of highly functionalized structures is discussed.