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Salt and Voltage Dependence of the Conductance Blockade Induced by Translocation of DNA and RecA Filaments Through Solid-state Nanopores

Amongst many other applications, solid-state nanopores – tiny holes in a thin membrane – can be used for rapid single-molecule high-throughput label-free detection of small samples of, for example, DNA or DNA-protein complexes. The interpretation of the current signal that one observes when DNA transverses a nanopore is a central point in all nanopore work. However, a complete and thorough understanding is still lacking.

Print publication date: 07 Sep 2012
Copyright year: 2013
Print ISBN: 978-1-84973-416-5
PDF eISBN: 978-1-84973-527-8
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