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The Effect of Disulphide Bond Disruption on the Barrier Integrity of the Human Nail

Onychomycosis is the fungal infection of the nail and accounts for approximately 50% of all nail disorders [1]. The prevalence of onychomycosis is increasing and currently up to 10 % of people in the UK and US are reported to be affected by this condition [2,3]. It can be both physically and psychologically debilitating during the most progressive stages of the disease [4,5]. Fungi (most frequently Trichophyton rubrum and Trichophyton mentagrophytes), moulds (Scytalidium spp, Scopulariopsis spp, Fusarium spp, Acremonium spp, Onychocola canadensis) and yeasts (Candida spp) can be co-resident in a diseased nail and hence not every nail can be considered as being populated by the same community of species.

Publication details


Print publication date
06 Dec 2013
Copyright year
2014
Print ISBN
978-1-84973-398-4
PDF eISBN
978-1-84973-463-9
From the book series:
Issues in Toxicology