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Chapter 11

Nuclear Magnetic Resonance Case Studies in Marine Natural Products

Marine natural products represent a remarkably diverse array of structure classes, many featuring “first-in-class” carbon skeletons, heterocycles, and functionality, further elaborated with stereochemical complexity. Typically isolated in low yields from complex natural extracts, these metabolites can be unstable and prone to rearrangement and/or degradation during handling and storage, and particularly during spectroscopic analysis. This chapter uses a number of case studies from the authors’ laboratory to illustrate some of the challenges encountered and benefits that arise from using NMR in the structure elucidation of marine natural products.

Publication details


Print publication date
14 Dec 2016
Copyright year
2017
Print ISBN
978-1-84973-393-9
PDF eISBN
978-1-84973-468-4
ePub eISBN
978-1-78801-072-6