Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 22nd May 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.

All chapters
Previous chapter Next chapter

Chapter 5

Docking, Screening and Selectivity Prediction for Small-molecule Nuclear Receptor Modulators

Nuclear receptors (NRs) represent a family of ligand-dependent transcription factors, united by common functional mechanism and domain architecture. At least 13% of marketed drugs target NRs.1 The two key domains, the ligand-binding domain (LBD) and the DNA-binding domain (DBD), are conserved in mos...
Print publication date: 02 Nov 2012
Copyright year: 2013
Print ISBN: 978-1-84973-364-9
PDF eISBN: 978-1-84973-535-3
From the book series:
Drug Discovery