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Chapter 1

Nuclear Receptors: Connecting Human Health to the Environment

Nuclear receptors (NRs) are evolutionary conserved proteins whose encoding genes are expressed in the animal kingdom (metazoans); they are also present in animals that do not have any endocrine system.1 NRs function as transcription factors activated by small (<1000 Da) lipophilic compounds able to ...
Print publication date: 02 Nov 2012
Copyright year: 2013
Print ISBN: 978-1-84973-364-9
PDF eISBN: 978-1-84973-535-3
From the book series:
Drug Discovery