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Chapter 2.1

Nanostructures Overcoming the Intestinal Barrier: Physiological Considerations and Mechanistic Issues

Only two peptides have been licensed to date for oral delivery, desmopressin and cyclosporine (CsA). The synthetic V2 receptor agonist, desmopressin, is exceptionally potent, stable and relatively cheap to synthesize, and thus its oral bioavailability (F) of 0.16% is still commercially acceptable.1 ...
Print publication date: 30 Jul 2012
Copyright year: 2012
Print ISBN: 978-1-84973-363-2
PDF eISBN: 978-1-84973-529-2
From the book series:
Drug Discovery