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Chapter 2.1

Nanostructures Overcoming the Intestinal Barrier: Physiological Considerations and Mechanistic Issues

Only two peptides have been licensed to date for oral delivery, desmopressin and cyclosporine (CsA). The synthetic V2 receptor agonist, desmopressin, is exceptionally potent, stable and relatively cheap to synthesize, and thus its oral bioavailability (F) of 0.16% is still commercially acceptable.1 ...

Publication details


Print publication date
30 Jul 2012
Copyright year
2012
Print ISBN
978-1-84973-363-2
PDF eISBN
978-1-84973-529-2
From the book series:
Drug Discovery