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Chapter 13

Computational Strategies and Challenges for Targeting Protein–Protein Interactions with Small Molecules

In biological systems, function and malfunction ultimately originates from interacting rather than isolated molecules. As such, most cellular processes are carried out by multiprotein complexes,1 and the organization of the ensemble of expressed proteins into functional units results in complex prot...
Print publication date: 15 Jun 2012
Copyright year: 2012
Print ISBN: 978-1-84973-353-3
PDF eISBN: 978-1-84973-537-7
From the book series:
Drug Discovery