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Chapter 6

Pharmacophore Models in Drug Design

A pharmacophore is an abstract concept introduced by Kier in the late 1960s1 that is used to describe the steric arrangement of functional groups that enable a small molecule to bind to a receptor. The IUPAC definition is as follows: “A pharmacophore is the ensemble of steric and electronic features...
Print publication date: 15 Jun 2012
Copyright year: 2012
Print ISBN: 978-1-84973-353-3
PDF eISBN: 978-1-84973-537-7
From the book series:
Drug Discovery