Chapter 6: Fluorous Catalysts

The presence of extended fluorocarbon domains in the structure of chiral catalysts and ligands can trigger unusual solubility properties, phase behaviour or interactions with solid supports, which can be used to achieve their efficient separation from organic products. In the last decade, the many reaction/separation/recycling options offered by the use of chiral fluorous catalysts, including their solubilization in supercritical or compressed CO₂, have been explored in several fundamental asymmetric catalytic transformations. A broad overview of the achievements and problems connected with the application of fluorous chiral catalytic systems is presented in this chapter.