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Chapter 8

Allosteric Activators of Glucokinase (GK) for the Treatment of Type 2 Diabetes

Kinases, also referred to as phosphotransferases, are key modulators of a variety of cellular and biochemical pathways and are known to phosphorylate a host of substrates including lipids, proteins, nucleotides, aminoacids and carbohydrates, thereby facilitating intracellular signaling. From a tradi...

Publication details


Print publication date
06 Dec 2011
Copyright year
2012
Print ISBN
978-1-84973-174-4
PDF eISBN
978-1-84973-355-7
From the book series:
Drug Discovery