Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 21st October 2020 from 07:00 AM to 07:00 PM (BST).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


All chapters
Previous chapter Next chapter

Chapter 1

Pharmaceutical Salts and Co-crystals: Retrospect and Prospects

Every new field in chemistry needs a link to an application of commercial and practical interest to sustain interest. Each such field generates a whole new set of ideas, paradigms and models. These concepts need to be tested in as wide a variety of forums as possible because their generality has to be proven. The industrial enterprise has always provided an excellent testing ground for new ideas in the chemical sciences. Many fundamental concepts took root because of an impetus from industry, the most spectacular ones being the discovery of stereochemistry by Pasteur, Haber's process for nitrogen fixation, and the birth of polymer chemistry starting with the production of synthetic rubber from isoprene. The subject of crystal engineering appeared in its modern manifestation in the late 1980s and the early 1990s. Two important branches of this subject emerged. The field of co-ordination polymers quickly found its practical application in the gas absorption properties of metal-organic framework compounds. The field of organic crystal engineering found it, a little later, in the area of pharmaceutical co-crystals and salts. The chapters in this book illustrate the tremendous growth in this area during the past decade.

Publication details


Print publication date
14 Nov 2011
Copyright year
2012
Print ISBN
978-1-84973-158-4
PDF eISBN
978-1-84973-350-2
From the book series:
Drug Discovery