Replacement of Hazardous Solvents and Reagents in Analytical Chemistry
This chapter presents numerous alternatives to solvents and reagents for analytical chemistry. Solvents alone often account for most of the waste generated by analytical methods, especially through sample preparation and mobile phases. Efforts to reduce the amount of solvent have been the focus of other chapters and literature. The situation is not as dire as it once was. Particularly hazardous solvents, like benzene and chloroform, and reagents that are persistent, bioaccumulative, and toxic (PBT) compounds, have for the most part been replaced by less hazardous alternatives. There is an increasing awareness of green chemistry across the disciplines, including analytical chemistry, and actions are being taken to improve the environmental footprint of analysis.