Detection of Damage to DNA Using Electrochemical and Piezoelectric DNA-Based Biosensors
DNA is an electroactive compound and electroanalysis is considered to be a fundamental technique in studying DNA damage, detecting low levels of genotoxic substances, and studying their effects on DNA. Moreover, electroanalysis can be used to evaluate the DNA protection (antioxidative) capacity of various natural and synthetic substances. This chapter deals entirely with the use of electrochemical and piezoelectric DNA biosensors to detect, induce, and control DNA damage. The state of the art in detection principles and applications of DNA biosensors in recent years is reviewed.