P-Stereogenic Compounds Derived from Enantiopure Heterocycles
This chapter is devoted to the preparation of optically pure P-stereogenic phosphines starting from some of the heterocycles described in chapter 3. It gives a detailed account on the Jugé-Stephan method, starting from oxazaphospholidines prepared from ephedrine. The scope, extensions and limitations of the method are discussed. Other similar methodologies are also described.