Air Pollution and Diabetes
Numerous studies have found evidence suggesting that diabetics are particularly susceptible to the health effects of air pollution. While a number of plausible pathways related to inflammation and oxidative stress have been proposed, the mechanisms underlying the observed associations remain unclear, both because of the complex nature of diabetes etiology as well as the heterogeneous composition of air pollution. This review attempts to address the major health-related areas in which diabetes has been demonstrated to influence vulnerability to ambient pollution exposures, and to provide an overview of proposed mechanisms. Given the extent of the public health and medical costs related to diabetes treatment and prevention strategies, as well as the projected increase in prevalence of this disease, identification of environmental risk factors which can be regulated may be an important public health intervention.