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Chapter 9

Use of Functionalized Magnetic Nanoparticles in Modern Separation Techniques

Nanotechnology has emerged as an integration of innovative development and applied management of materials at the nanoscale. It has been inclusively developed in multidisciplinary fields like industrial waste management, water, and soil pollution management, biomedical, and biochemistry. Analytical chemistry and nanotechnology in conjunction have proven to be very effective in simplifying various analytical chemical processes. The analytical techniques have improved the existing methodologies through development of functionalized magnetic nanomaterials, magnetic composites etc. The use of nanoparticles (NPs) for the separation of biomolecules and biochemical assays has given efficient results, leading to higher employment of NPs in separation techniques since the last decade. Nanomaterials in the size range of 1–2 nm have found applications in chromatographic techniques including conventional high-performance liquid chromatography (HPLC), gas chromatography (GC), etc. Some of the advantages of magnetic nanoparticles (MNPs) include the controllable fluid motion in microsystems for chromatographical separation methodologies. Moreover, MNPs also remain unaffected by variables like concentration, pH and surface charges, etc. Thus, a very wide spectrum of academics and researchers have acknowledged the benefits of functionalized MNPs, and promoted their employment as highly efficient modern separation tools.

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04 Aug 2021
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