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Chapter 10

Minimalistic Peptide Self-assembly into Supramolecular Biomaterials

Short peptides are attractive building blocks for supramolecular biomaterials for their low-cost, scalability of production and purification, possibility to encode biological messages, and to be processed by enzymes to fine-tune their lifetime toward controlled biodegradation. Over the last few decades, great progress has been made in the understanding of these building blocks for their tailored design to a variety of biological applications. This chapter reviews the design strategies to achieve hydrogels that have been applied to address a variety of biomedical needs. As more knowledge has been gathered in the field, a higher complexity could be achieved, for instance to target subcellular organelles, specific cells, and even to stimulate the immune response. Overall, self-assembling short peptides are reaching their full potential and have opened the gates to new paradigms in therapy to realize futuristic medicine.

Publication details

Print publication date
11 Jun 2021
Copyright year
2021
Print ISBN
978-1-78801-757-2
PDF eISBN
978-1-83916-112-4
ePub eISBN
978-1-83916-113-1

From the book series:
Soft Matter Series