Skip Nav Destination
Chemical Biology
The Discovery and Utility of Chemical Probes in Target Discovery
Edited by
Saleta Vazquez Rodriguez
Saleta Vazquez Rodriguez
University of Oxford, UK
Search for other works by this author on:
Hardback ISBN:
978-1-78801-589-9
PDF ISBN:
978-1-83916-074-5
EPUB ISBN:
978-1-83916-084-4
Special Collection:
2020 ebook collection
Series:
Chemical Biology
No. of Pages:
326
Publication date:
17 Nov 2020
Book Chapter
CHAPTER 2: DNA-encoded Chemistry and Its Use in Discovering Chemical Probes
By
Anthony D. Keefe
Anthony D. Keefe
Search for other works by this author on:
-
Published:17 Nov 2020
-
Special Collection: 2020 ebook collectionSeries: Chemical Biology
Citation
A. D. Keefe, in The Discovery and Utility of Chemical Probes in Target Discovery, ed. P. Brennan and S. V. Rodriguez, The Royal Society of Chemistry, 2020, pp. 14-38.
Download citation file:
This chapter first introduces the concept of a DNA-encoded chemical library and describes the different forms that such libraries may take as a result of the different methodologies that may be used to create them. Methods by which such libraries can be used to discover specific engagers of arbitrary protein targets are then discussed, followed by a review of literature examples of chemical probes discovered from within such libraries.
You do not currently have access to this chapter, but see below options to check access via your institution or sign in to purchase.
Digital access
$64.60
