Jump to main content
Jump to site search
SCHEDULED MAINTENANCE Close the message box

Maintenance work is planned for Monday 16 August 2021 from 07:00 to 23:59 (BST).

Website performance may be temporarily affected and you may not be able to access some PDFs or images. If this does happen, refreshing your web browser should resolve the issue. We apologise for any inconvenience this might cause and thank you for your patience.


All chapters

Chapter 20

The Adverse Outcome Pathways Approach

The toxicity – or any other biological activity – of a chemical is triggered by a direct action of some kind at a molecular level but what the observed harmful outcome is, if any, depends on a chain of events from the molecular level to the cell, the organ containing it, and the whole organism. To be fully-effective, a prediction model needs to take into account the whole chain of events – the adverse outcome pathway.

Publication details


Print publication date
15 Feb 2019
Copyright year
2019
Print ISBN
978-1-78801-471-7
PDF eISBN
978-1-78801-618-6
ePub eISBN
978-1-78801-742-8