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Intrinsically disordered proteins (IDPs) studied by EPR and in-cell EPR

Intrinsically disordered proteins (IDPs) play important physiological, but also disease-related roles. In order to understand the function and malfunction of proteins of this class, electron paramagnetic resonance (EPR) spectroscopy has proven to be a valuable tool, allowing investigation of the protein structural ensembles upon interaction with the environment. This review focuses on the IDPs tau and α-synuclein and gives an overview over recent EPR studies performed with these proteins.

Print publication date: 06 Nov 2018
Copyright year: 2019
Print ISBN: 978-1-78801-372-7
PDF eISBN: 978-1-78801-388-8
ePub eISBN: 978-1-78801-688-9