Nucleation and Crystal Growth in Continuous Crystallization
This chapter discusses the fundamental aspects of nucleation and particle formation in the continuous crystallization context, with a main focus on nucleation and crystal growth. The classic crystallization phenomena, fundamental, thermodynamic or kinetic driven, will not be covered here. The primary and secondary nucleation, and some methods of nuclei generation in continuous crystallization are discussed in this chapter. The performance of continuous crystallization processes and challenges with process kinetics and control (such as seeding, mixing, and process dynamics) are also addressed in this chapter.