Synthetically Useful Glycosyltransferases for the Access of Mammalian Glycomes
Glycans play key roles in biological processes. However, complex glycans are not easily accessible and affordable to support diverse functional study. In the efforts of glycan syntheses, one of the most practical approaches is the strategy that employs glycosyltransferases (GTs) – the natural catalysts for glycan biosynthesis. This chapter summarizes the synthetically useful bacterial and mammalian GTs for the preparation of glycans, with an emphasis on mammalian glycans.