Introduction: Glycome and the Glyco-toolbox
Carbohydrates, nucleic acids, and proteins comprise the three major macromolecules found in mammalian systems. As genomics and proteomics represent the studies of nucleic acids and proteins, respectively, the term “glycomics” describes the systematic study of the complete repertoire of glycans. Unlike genomics and proteomics, which both have methods for sequencing, automatic synthesis, and amplification, glycomics is comparatively underdeveloped. In this chapter, the challenge, opportunities, and achievement of glycomics and the development of the “glyco-toolbox” will be discussed.