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Non-target/High-resolution Mass Spectrometric Strategies Combined with Proper Data Handling and Software Elaboration Applied to Food Contact Materials Issues

Interest in the identification of potential migrants, including non-intentionally added substances (NIASs), referring to objects intended to come into contact with food, has recently been growing. Such substances have been found at trace levels in simulants and in food products placed in contact with plastic materials. However, the identification of unknown migrants from food contact materials (FCMs) is an issue since neither chemical or spectral databases nor analytical standards are available. To overcome such a challenge, the use of highly sensitive analytical techniques in combination with software tools for data acquisition and data treatment is critical to achieve increased confidence in peak assignments. This chapter presents a review of the data acquisition modes and the data handling used for the identification/characterization of migrants from FCMs, particularly based on the application of liquid chromatography coupled with high-resolution accurate mass spectrometry (LC-HRAMS) methods.

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Print publication date
25 Jan 2019
Copyright year
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ePub eISBN