Introduction to Kinase Drug Discovery – Modern Approaches
The first edition of the “Kinase Drug Discovery (RSC Drug Discovery Series)” book was published in December 2011. Our aim with that book was to cover and reflect on the rich and diverse opportunities and challenges within this fascinating target class. Just 7 years later the field of kinase research has become even more significant for medicinal chemistry. The number of approved drugs that target kinases has exploded in number and the scientific scope of the field has expanded significantly; some of the most interesting areas of research in kinase drug discovery today were relatively minor fields previously. Consequently, we felt it was important to publish a new (second) edition that captures the trends and “hot topics” that are of interest to the medicinal chemist today and that are likely to remain key areas of focus for kinase drug discovery research over the next decade.