Contents
Ilona Pysz, Paul. J. M. Jackson and David E. Thurston
Introduction to Cancer 1
Cancer Treatments 3
Antibody–Drug Conjugates (ADCs) 4
Mechanism of Action of ADCs 7
Antibody Selection 10
Linker Design 14
Payload Selection 16
Conjugation of Payload 18
Analytical Characterisation of ADCs 24
Conclusions...