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Chapter 13

Chemical Protein Synthesis: Strategies and Biological Applications

Synthetic protein chemistry enables precise control of the chemical makeup of proteins and facilitates the incorporation of new functionalities and connectivities. This chapter covers the principles of protein synthesis, by solid-phase peptide synthesis one amino acid at a time and through expedient fragment assembly via convergent methods. General applications of synthetic proteins, as well as a series of case studies that demonstrate the utility and versatility of synthetic protein chemistry for solving biological problems are discussed.

Publication details


Print publication date
28 Aug 2018
Copyright year
2018
Print ISBN
978-1-78262-948-1
PDF eISBN
978-1-78801-280-5
ePub eISBN
978-1-78801-507-3
From the book series:
Chemical Biology