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Molecularly Imprinted Polymer Sensor Arrays

This chapter provides an updated review of research about chemosensor arrays and assays assembled from molecularly imprinted polymers (MIPs) and imprinted materials. The molecular imprinting process provides rapid and inexpensive access to tailorable molecular recognition elements for sensing applications. However, chemosensors based on individual MIPs typically reveal low selectivity and high cross-reactivity. Assembling multiple MIPs into an array presents a convenient and effective solution to this problem. The binding pattern of each analyte to an array of MIPs can provide a unique fingerprint which can be classified using multivariate pattern recognition algorithms. In this chapter, key aspects in designing and developing MIP sensor arrays will be discussed, including the choice of template and monomer, polymer matrix and morphology, signaling mechanisms, and statistical data analysis. Selected examples from the literature are presented to highlight unique advantages and applications of the MIP chemosensor array as well as future problems and challenges.

Publication details

Print publication date
26 Apr 2018
Copyright year
Print ISBN
ePub eISBN

From the book series:
Polymer Chemistry Series