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Chapter 11

Pd-catalysed Cross-couplings for the Pharmaceutical Sector and a Move to Cutting-edge C–H Bond Functionalization: Is Palladium Simply Too Precious?

The case is made for Pd being a critical metal catalyst for a variety of key pharmaceutical sector reactions. There is a need to make such processes more sustainable, e.g. through catalyst recycling, use of lower catalyst loadings and deployment in sustainable C–H activation reactions that avoid high molecular weight waste side-products. Understanding the role played by higher order Pd species (nanoparticles and clusters) is essential in the future. These and related aspects are discussed within this chapter.

Print publication date: 14 Mar 2016
Copyright year: 2016
Print ISBN: 978-1-78262-467-7
PDF eISBN: 978-1-78262-594-0
ePub eISBN: 978-1-78262-747-0
From the book series:
Green Chemistry Series