Solvents made from renewable feedstocks offer an opportunity to move towards greater sustainability of products and processes. Sources of bio-based solvents are introduced in this chapter, as well as the certification available to demonstrate the bio-based content of a solvent or solvent-based product. Also contained in the chapter is a summary of the properties of the most established (commercialised) bio-based solvents. The future of solvent use will also incorporate alternatives to conventional volatile organic solvents. It is important to understand the limitations of aqueous solvents, supercritical fluids, ionic liquids and deep eutectic solvents, and advance our understanding of their social, economic, and environmental sustainability. Until the sustainability and economic viability of neoteric solvents is unresolved, speciality petrochemical solvents designed to be high performance yet environmentally benign will play a growing role in contemporary solvent use patterns. These solvents, completely compatible with current solvent technologies, are explained alongside the neoteric solvent classes.