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Chapter 16

Genotoxic Effects in Peripheral Blood and Sperm in Humans in Healthy Individuals and Those with Disease States

The comet assay is one of the most versatile tools in toxicology today and can be used to measure responses in both diploid (peripheral blood lymphocytes) and haploid (sperm) primary cells in humans. This chapter will discuss how these cells are employed to determine if they have differential responses to chemical and physical agents in healthy and disease-state individuals and how such information can be of use to man.

Print publication date: 07 Oct 2016
Copyright year: 2017
Print ISBN: 978-1-78262-287-1
PDF eISBN: 978-1-78262-289-5
ePub eISBN: 978-1-78262-915-3
From the book series:
Issues in Toxicology