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Carbohydrate–carbohydrate interaction: from hypothesis to confirmation

Carbohydrates play important roles in a wide range of biological processes. Since the first hypothesis about carbohydrate–carbohydrate interaction (CCI) was proposed by Hakomori et al., an increasing interest has been placed on CCI, using a variety of techniques. Based on all these studies, Lewisx–Lewisx interaction (a typical CCI) has been now confirmed to be specific, homotypic, and mediated by the presence of divalent cations such as Ca2+. In this review, a detailed overview of the process from hypothesis to confirmation of carbohydrate–carbohydrate interaction is summarized.

Publication details

Print publication date
04 Dec 2015
Copyright year
2016
Print ISBN
978-1-78262-121-8
PDF eISBN
978-1-78262-060-0
ePub eISBN
978-1-78262-795-1

From the book series:
SPR - Carbohydrate Chemistry