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CHAPTER 10

Tungsten-Containing Enzymes

This review on the biochemistry of W-containing enzymes, or tungstoenzymes, starts and ends with the question: “why tungsten?” Structural, kinetic and mechanistic properties of the enzymes are evaluated and related to the common division into two families and several classes. Experimental inconsistencies are identified and proposed models are questioned as a way to determine what we now know and what we still should find out in order to be able to address the “why tungsten?” question in sufficient (bio)chemical depth. Specific recommendations are made to re-direct research on tungstoenzymes in order to cover key dark spots in our present knowledge.

Publication details


Print publication date
28 Sep 2016
Copyright year
2017
Print ISBN
978-1-78262-089-1
PDF eISBN
978-1-78262-391-5
ePub eISBN
978-1-78262-881-1
From the book series:
Metallobiology