New Analytical Approaches for the Detection of Micropollutants in Natural Waters: Identification of 3,5-Dichloro-4-Hydroxybenzene Sulfonic Acid as an Unknown Persistent Pollutant
The analysis of emerging contaminants in natural water sources has been based primarily on the analysis of “known unknowns”. These are compounds whose identities are known and several of their chemical or physical properties are tabulated in a database. Here we present an analytical strategy for the determination of pollutants with unknown structures based on liquid chromatography and full scan tandem mass spectrometry with detection based on structural features that suggest the potential toxicity of the unknown. We are using precursor ion scanning for