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Chapter 18

The Impact of Protein Kinase Structures on Drug Discovery

Protein phosphorylation regulates many aspects of cellular functions. Abnormal phosphorylation is implicated in a myriad of human diseases. Eukaryotic protein kinases make up an unusually large family of proteins related by a homologous catalytic domain (known as the protein kinase domain). The sequ...

Publication details


Print publication date
26 Oct 2007
Copyright year
2007
Print ISBN
978-0-85404-365-1
PDF eISBN
978-1-84755-796-4
From the book series:
RSC Biomolecular Sciences