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Chapter 17

A Link Means a Lot: Disulfide Tethering in Structure-Based Drug Design

Tethering is a disulfide-based drug-discovery technology that grew out of the era when combinatorial chemistry was a burgeoning new development. What separates Tethering from other combinatorial approaches is its site-directed nature. The disulfide link that is formed allows a wide variety of advant...

Publication details


Print publication date
26 Oct 2007
Copyright year
2007
Print ISBN
978-0-85404-365-1
PDF eISBN
978-1-84755-796-4
From the book series:
RSC Biomolecular Sciences