Computational Prediction of Aqueous Solubility, Oral Bioavailability, P450 Activity and hERG Channel Blockade
Over the past decade or so, the pharmaceutical industry has come under increasing pressure to make the drug-discovery process more efficient and thus more cost-effective. Partly in response to this, new technologies have been enthusiastically embraced: the “omics” (e.g. genomics, proteomics) promisi...