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Chapter 6

Knowledge-Based Methods in Structure-Based Design

Knowledge-based approaches work on the (reasonable) assumption that the relative frequencies of different interaction geometries observed in a range of experimental structures are indicative of the relative stability of these geometries. This idea even pre-dates the start of the computerized structu...

Publication details


Print publication date
26 Oct 2007
Copyright year
2007
Print ISBN
978-0-85404-365-1
PDF eISBN
978-1-84755-796-4
From the book series:
RSC Biomolecular Sciences