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Chapter 4

Application and Limitations of X-Ray Crystallographic Data in Structure-Guided Ligand and Drug Design

There can be no doubt that drug discovery is an increasingly complex, risky and expensive business. Recent estimates place the cost of delivering a drug to the marketplace at greater than $800 000 000,1 with only one in ten compounds that enter clinical development actually making it to the market. ...

Publication details


Print publication date
26 Oct 2007
Copyright year
2007
Print ISBN
978-0-85404-365-1
PDF eISBN
978-1-84755-796-4
From the book series:
RSC Biomolecular Sciences