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Chapter 13

DNA Nucleases

This chapter reviews structural studies of DNA nucleases that cleave the backbone of DNA at the P–O3′ bond, utilizing water as a nucleophile (with one exception) and leave 5′phosphate and 3′OH ends. The three-dimensional crystal structures of over 90 different nucleases have been solved to date. As ...

Publication details


Print publication date
22 Apr 2008
Copyright year
2008
Print ISBN
978-0-85404-272-2
PDF eISBN
978-1-84755-826-8
From the book series:
RSC Biomolecular Sciences