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Chapter 14

Peptidyl Transferase Mechanism: The Ribosome as a Ribozyme

Most natural ribozymes catalyze phosphoryl transfer reactions that require the activation of a ribose hydroxyl group (the nucleolytic ribozymes; self-splicing introns; perhaps the spliceosome) or a water molecule (RNase P) for nucleophilic attack of a phosphodiester bond.1 However, the most abundant...

Publication details


Print publication date
15 Nov 2007
Copyright year
2007
Print ISBN
978-0-85404-253-1
PDF eISBN
978-1-84755-798-8
From the book series:
RSC Biomolecular Sciences