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Chapter 6

Development and Applications of the Comet-FISH Assay for the Study of DNA Damage and Repair

The single-cell gel electrophoresis (SCGE) assay was first reported by Östling and Johanson1 in 1984 as a technique for visualising the migration of DNA containing strand breaks in individual agarose-embedded cells under electrophoretic conditions. A few years later, Singh et al.2 used a similar met...
Print publication date: 27 Aug 2009
Copyright year: 2009
Print ISBN: 978-0-85404-199-2
PDF eISBN: 978-1-84755-974-6
From the book series:
Issues in Toxicology