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Chapter 2

Detection of Oxidised DNA Using DNA Repair Enzymes

Cells are continuously exposed to endogenous and exogenous agents that damage DNA. One of the most common kinds of damage is oxidation. Normal cellular metabolism produces reactive oxygen species (ROS) that interact with the DNA creating oxidised bases. These ROS include hydrogen peroxide, superoxid...

Publication details


Print publication date
27 Aug 2009
Copyright year
2009
Print ISBN
978-0-85404-199-2
PDF eISBN
978-1-84755-974-6
From the book series:
Issues in Toxicology