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Chapter 11

Single Cell Analysis of TSE-infected Neurons

Scrapie, a rare neurodegenerative disorder of the central nervous system, is characterized by the accumulation of a β-sheet rich protein, called PrPSc or scrapie-associated prion protein, primarily in the central and peripheral nervous system. First described in 1732 in sheep, the disease belongs to...

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15 Dec 2010
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