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Chapter 7

Substrate Loading, Nucleotide Addition, and Translocation by RNA Polymerase

After the RNA polymerase (RNAP) holoenzyme commences RNA synthesis, the initiation complex isomerizes into the elongation complex (EC) in which the RNAP translocates the template DNA and synthesizes RNA transcripts of up to ∼104(bacterial) to ∼106(eukaryotic) nucleotides. At the ends of transcriptio...
Print publication date: 10 Mar 2009
Copyright year: 2009
Print ISBN: 978-0-85404-134-3
PDF eISBN: 978-1-84755-998-2
From the book series:
RSC Biomolecular Sciences