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Chapter 7

Substrate Loading, Nucleotide Addition, and Translocation by RNA Polymerase

After the RNA polymerase (RNAP) holoenzyme commences RNA synthesis, the initiation complex isomerizes into the elongation complex (EC) in which the RNAP translocates the template DNA and synthesizes RNA transcripts of up to ∼104(bacterial) to ∼106(eukaryotic) nucleotides. At the ends of transcriptio...

Publication details


Print publication date
10 Mar 2009
Copyright year
2009
Print ISBN
978-0-85404-134-3
PDF eISBN
978-1-84755-998-2
From the book series:
RSC Biomolecular Sciences