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Chapter 9

Probing Coupled Motions in Enzymatic Hydrogen Tunnelling Reactions: Beyond Temperature-Dependence Studies of Kinetic Isotope Effects

The potential importance of protein dynamics coupled to tunnelling in enzymatic systems has been highlighted in contributions elsewhere in this volume (Chapters 6 and 8 ). The role of dynamical processes, and how these could have evolved, remains a key question in enzymology.1–4 Of particular intere...
Print publication date: 27 Mar 2009
Copyright year: 2009
Print ISBN: 978-0-85404-122-0
PDF eISBN: 978-1-84755-997-5
From the book series:
RSC Biomolecular Sciences